A woman reflects on the challenges of maintaining her weight loss after coming off the drug Mounjaro, considering the temptation of holiday treats and the rising trend of microdosing with weight-loss medications.
The Stilton and crackers were always going to be my toughest test. Or possibly the yule log. The profiteroles. The Baileys… Coming off the weight-loss jab Mounjaro just before Christmas was surely inviting failure. From August to October, I'd dropped two stone and achieved my target weight of 8st 12lbs. I could slip into a wisp of a cocktail dress and yet, as I wrote in this paper in December, I was dreading the start of the party season and, in truth, Christmas itself.
My diary was more full than usual and every engagement involved temptation: a gathering catered by two top chefs, post-carol-service wine and mince pies, lunch at the home of my favourite cookbook writer, canapes at a stately home, and our own traditional New Year's Eve fondue and raclette party. On it went. Eat me, eat me, eat me. Did I have the strength to resist? Meanwhile, in my fridge at home sat another form of temptation. I took my final dose of Mounjaro in October. But I still had one syringe pen left, in date until February 2025. It sat in my fridge calling to me just as much as the Stilton, for with one jab – indeed, one so-called 'microdose' – I knew I could make all this Christmas 'food noise' disappear. Microdosing with weight- loss jabs like Mounjaro is an increasingly common tactic. Some medics now recommend you spend up to a year on a weekly 2.5mg of the drug after coming off the full dose. (The full dose is different for everyone – I never went higher than 7.5mg.) The theory here, in simple terms, is that your body has a 'set point' it strives to return to after any form of weight loss and, unless you stick rigidly to healthy eating and daily exercise, three out of four people pile the pounds back on. It's now thought that staying on a small maintenance dose for 12 months gives your body time to readjust to a new, slimmer 'set point', meaning you're more likely to stick at it
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