The transmission of SARS-CoV-2 in hospitals and its impact on the dynamics of the COVID-19 pandemic.
By Pooja Toshniwal PahariaOct 23 2023Reviewed by Benedette Cuffari, M.Sc. In a recent study in Nature, researchers investigate the transmission of the severe acute respiratory syndrome coronavirus 2 in hospitals and its impact on the dynamics of the coronavirus disease 2019 pandemic.
About the study The researchers quantified within-hospital transmission, evaluated likely pathways of viral transmission and factors associated with heightened transmission risk, and investigated the wider dynamical consequences using information provided by 145 National Health Service hospital trusts providing acute care in England, excluding those providing exclusively pediatric care. The trusts included 356 hospitals with a total capacity of 100,000 beds and 859,000 HCWs in full-time jobs.
The data, collectively with other datasets of national-level information, were used to estimate nosocomial COVID-19 case counts in England between June 2020 to February 2021, nosocomial SARS-CoV-2 transmission routes, and variables influencing the transmission. The researchers investigated the influence of nosocomial COVID-19 on the efficacy of community-level lockdowns in preventing infections by modeling community and hospital dynamics.
Additional PCR testing for asymptomatic individuals on hospitalization days three and six raised the proportion found to 33% but did not significantly change the percentage of definitely healthcare-related infections. The incorporation of PCR testing for all COVID-19 patients at one-week intervals to symptomatic PCR tests increased the percentage of diagnosed nosocomial infections to 44% and definitely healthcare-related infections to 17%.
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