‘There’s a real bias’: what do we know about anti-obesity drugs in Australia?

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‘There’s a real bias’: what do we know about anti-obesity drugs in Australia?
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Demand for the ‘Hollywood skinny jab’ has prompted worldwide shortages of Ozempic, but a new class of drugs has challenged the way we approach obesity

, and a shortage of one particular product – semaglutide, marketed in Australia as Ozempic and approved only for the treatment of type 2 diabetes – possibly due to its popularity with celebrities and influencers. The drug has become so widely known in popular culture that it was the subject of jokes at the recent Oscars.

“All that reporting about the Hollywood skinny jab and about people using it to just lose a couple of kilos; if that is happening, I don’t know where those people are getting a medical practitioner to prescribe them that medication,” says Associate Prof Priya Sumithran, head of obesity medicine at AustinFor people with obesity, the majority of whom will undertake a difficult, uncomfortable and often unsuccessful journey to manage their weight solely through diet and exercise, or for those...

Living in a society saturated with cheap, high-fat, high-energy food adds to the challenges for people trying to lose weight.“Although many people can successfully lose weight, for most people they regain the weight they’ve lost, and then the amount of weight that they keep off long-term is actually very, very modest,” says endocrinologist Associate ProfThe reason is metabolic adaptation: when people with overweight or obesity try to lose weight, their body fights back hard to keep it.

“If you’re living in that environment, you’re trying to lose weight, you’re more efficient at using energy, your hormones are telling you you’re hungry, all that food is available, it’s just really easy to slip back,” Hocking says. “It’s a struggle for people and that’s why we do need these highly effective therapies particularly for people who have both obesity and health issues.”

The anti-obesity drugs available in Australia today – some of which are approved for the treatment of obesity, others for the treatment of type 2 diabetes – work in a variety of ways.

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