Transcranial ultrasound stimulation combines accuracy and reversibility, paving the way for innovative treatments of neurological and psychiatric disorders.
By Vijay Kumar MalesuReviewed by Lily Ramsey, LLMNov 1 2024 Exploring the potential of transcranial ultrasound stimulation to precisely target and treat brain circuit disorders noninvasively.
While structural brain abnormalities can be identified through imaging, functional mapping is far more complex. Current intervention methods, such as implants or focal lesions, are invasive and lack scalability. Advances in structural and functional mapping Recent advancements in neuroimaging have improved our understanding of both structural and functional abnormalities in the brain. Technologies such as magnetic resonance imaging allow detailed visualization of brain anatomy at millimeter-scale resolution, which is useful for diagnosing and planning treatments for conditions like Parkinson’s disease.
Related StoriesNoninvasive options like TMS and tDCS are safer but lack precision and may only reach superficial cortical regions. Furthermore, when these methods are combined with neuroimaging, compatibility issues can distort data, making it difficult to achieve precise brain mapping and safe interventions.
Additionally, focused ultrasound can create temperature changes in brain tissues, influencing neuronal activity and membrane properties. Additionally, early evidence suggests that TUS could reduce seizure frequency in epilepsy and cravings in substance use disorders when directed at specific brain regions. These applications demonstrate TUS's versatility and potential to provide personalized treatments for a range of disorders.
Ultrasound Brain Stimulation Cell Efficacy Frequency Imaging Implants Neuroimaging Neuromodulation Research Technology
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