Ethicist Art Caplan discusses transplantation using organs from animals, and the need to be clear to patients that these early-stage procedures are research rather than lifesaving efforts.
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Richard Slayman was a volunteer. He was dying because he had exhausted his options for dialysis. He was not a candidate, being deemed too sick, for a human kidney transplant, so he wasn't somebody that was going to be listed. Massachusetts General Hospital basically asked the US Food and Drug Administration if they could try and save this gentleman using the pig kidney as a last-ditch effort to try and save his life.
All that said, we don't have enough organs — and we're not going to have enough organs — to transplant for those in need next week, next month, or even the rest of this year. Thus, we get to the genetically engineered pigs. We do some of that work at NYU. Obviously, it's going on in other places. It's better to have protocols that are agreed upon by the centers that can do this in the earliest stages of pioneering this procedure. Then people know they're coming in as experimental subjects — not so much to get themselves rescued but as a way to contribute, as part of their dying, to what we know, what we understand, to make learning possible, and to go forward with this alternative source of organs from the pig.
The person who died at Mass General, Mr Slayman, did say, and his family said later, that they were proud that he could contribute to knowledge. They were proud that maybe the doctors learned and that the next patients would benefit from his, if you will, altruistic sacrifice.
Renal Failure Renal Insufficiency Kidney Insufficiency Kidney Failure Renal Impairment Heart Failure Transplantation Transplant Transplantation Of An Organ Organ Transplantation Organ Transplant Kidneys Hemodialysis Vascular Access Kidney Dialysis Renal Dialysis Haemodialysis New York Fellowship Fellows Residency Residents Heart Hospitals Massachusetts Medical Ethics
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