The Wagner mutiny was just the “tip of the iceberg” of internal opposition to Russia’s military leadership, an expert told theipaper, after a prominent general accused his superiors of betrayal as he was dismissed Euanobm reports
Chris Morris, a lecturer in strategic studies at the University of Portsmouth, toldGeneral Ivan Popov, the commander of the 58th army, said he was dismissed after speaking out about the problems faced by his troops “I for one am doubtful that Prigozhin would have embarked on that without a broad base of support from within the Russian security services and the Russian military.
“Now, Putin knows that these people are still out there, but there’s not much that you can do to address them. It ended with Mr Prigozhin calling his mercenaries back to their camps in exchange for an amnesty and permission to, though generals Gerasimov and Shoigu – both loyalists to Mr Putin – remained in post.
Mr Morris said the war effort would have to be in an “absolutely catastrophic” position for Mr Putin to turn on his close allies, even though they are largely responsible for Russian failures on the battlefield.
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Effects of intravenous administration of magnesium sulfate in propofol-based sedation for ERCP in elderly patients: a randomized, double-blind, placebo-controlled study - BMC GeriatricsBackground Propofol-based sedations are widely used in elderly patients for endoscopic retrograde cholangiopancreatography (ERCP) procedure, but respiratory depression and cardiovascular adverse events commonly occur. Magnesium administered intravenously can alleviate pain and decrease propofol requirements during surgery. We hypothesized that intravenous magnesium was used as adjuvant to propofol might be beneficial in elderly patients undergoing ERCP procedures. Methods Eighty patients aged from 65 to 79 years who were scheduled for ERCP were enrolled. All patients were intravenously administered 0.1 µg/kg sufentanil as premedication. The patients were randomized to receive either intravenous magnesium sulfate 40 mg/kg (group M, n = 40) or the same volume of normal saline (group N, n = 40) over 15 min before the start of sedation. Intraoperative sedation was provided by propofol. Total propofol requirement during ERCP was the primary outcome. Results The total propofol consumption were reduced by 21.4% in the group M compared with the group N (151.2 ± 53.3 mg vs. 192.3 ± 72.1 mg, P = 0.001). The incidences of respiratory depression episodes and involuntary movement were less in the group M than those in the group N (0/40 vs. 6/40, P = 0.011; 4/40 vs. 11/40, P = 0.045; respectively). In the group M, the patients experienced less pain than those in the group N at 30 min after the procedure (1 [0–1] vs. 2 [1–2], P | 0.001). Correspondingly, the patients’ satisfaction was clearly higher in the group M (P = 0.005). There was a tendency towards lower intraoperative heart rate and mean arterial pressure in group M. Conclusions A single bolus of 40 mg/kg of intravenous magnesium can significantly reduce propofol consumption during ERCP, with higher sedation success and lower adverse events. Trial Registration ID UMIN000044737. Registered 02/07/2021.
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