The human brain's remarkably prolonged development is unique among mammals and is thought to contribute to our advanced learning abilities.
Vlaams Instituut voor BiotechnologieOct 14 2024 The human brain's remarkably prolonged development is unique among mammals and is thought to contribute to our advanced learning abilities. Disruptions in this process may explain certain neurodevelopmental diseases. Now, a team of researchers led by Prof.
The lab of Pierre Vanderhaeghen at the VIB-KU Leuven Center for Brain & Disease Research previously discovered that the prolonged development of the human cerebral cortex is mainly due to human-specific molecular mechanisms in neurons. Now, they are investigating these molecular timers in human neurons.
To address this, Dr. Baptiste Libé-Philippot, a Postdoctoral Fellow in the Vanderhaeghen lab, switched off SRGA2B and SRGAP2C in human neurons, transplanted them into mouse brains, and carefully monitored synapse development over an 18-month period.
Evolution Genes Autism Cortex Disability DNA Gene Neuron Neurons Research Stem Cells Synapse
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