A joint research study conducted by the UAB and the UB has analyzed the relation between the genetic risk of having schizophrenia and mild subclinical traits in people of the general population.
Universitat Autònoma de Barcelona Feb 26 2025 According to the study, the way the genetic risk of having this disorder affects these subclinical traits is different in men and women. The research, published in Progress in Neuropsychopharmacology & Biological Psychiatry , highlights the importance of considering gender differences in this relation.
A collaborative and interdisciplinary research team led by Dr Neus Vidal-Barrantes from the UAB and Dr. Araceli Rosa from the UB, researchers at the CIBERSAM Mental Health Research Centre, has tackled this question by analyzing the role of sex in this relation between genetics and subclinical expressions of schizophrenia in a sample of almost 1200 university students. The study found no clear association between schizophrenia-related genetic load and subclinical traits.
Although no conclusive evidence was found of a strong shared genetic basis between schizophrenia and its subclinical phenotypes, this study opens new questions and directions for researching how genetic variants and environmental factors interact differentially according to sex.
Schizophrenia Genetics Mental Health Psychiatry Psychosis Research Schizotypy
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