Researchers at the University of Colorado School of Medicine are hopeful new research could prevent up to 130,000 unneeded fine-needle aspiration (FNA) biopsies of thyroid nodules and subsequent surgeries each year in the United States by better understanding the genetic risk associated with thyroid cancer.
Apr 1 2024University of Colorado Anschutz Medical Campus Researchers at the University of Colorado School of Medicine are hopeful new research could prevent up to 130,000 unneeded fine-needle aspiration biopsies of thyroid nodules and subsequent surgeries each year in the United States by better understanding the genetic risk associated with thyroid cancer.
Thyroid cancer is the most common endocrine malignancy, representing about 44,000 new cases and 1% of new cancer diagnoses each year. When a thyroid nodule is detected in a patient, it can be difficult to know whether it's benign or cancerous. The power of data The researchers will leverage biobanks across the world, including the biobank at the Colorado Center for Personalized Medicine, to create a dataset that wouldn't be possible otherwise.
"This is the future of personalized medicine research," he continues. "We want to be able to benefit from what the data world can collectively tell us, then bring it back into a setting with domain experts to derive the maximal benefit and ensure our results translate into clinical and medical impact."
The introduction of FNA biopsies then allowed pathologists to know whether a tumor was benign. It was a real improvement, Haugen says, and cut unnecessary surgeries by about half, but there's still more work to do to create better outcomes for patients, especially the 20% of people who receive inconclusive biopsy results.
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