Researchers from the University of Liverpool's Centre for Drug Safety Science have identified unpredicted T-cell immune responses to the adenoviral (Oxford/AstraZeneca and Janssen) COVID-19 vaccines, but not to the mRNA vaccines.
University of LiverpoolJul 19 2024 Researchers from the University of Liverpool's Centre for Drug Safety Science have identified unpredicted T-cell immune responses to the adenoviral COVID-19 vaccines, but not to the mRNA vaccines.
The study showed that between 90-95% of participants who donated blood samples unexpectedly produced strong T-cell responses following exposure to the adenoviral vaccines in a laboratory setting. This new finding of strong T cell responses in pre-pandemic blood samples is therefore unexpected and suggests that there is widespread cross-reactivity between the adenoviruses used in the vaccines and the adenoviruses that naturally circulate at high levels in the human population.
Related StoriesThis study was part of the Thrombotic Thrombocytopenia Syndrome Consortium, supported in late 2021 by the National Institute for Health Research and backed by government funding from the Vaccine Taskforce to understand the reasons why there were rare instances of blood clotting with low platelets in some people who received the AstraZeneca and Janssen vaccines.
Antibodies Bacteria Blood Cell Covid-19 Efficacy Frequency Laboratory Pandemic Platelets Syndrome T-Cell Vaccine Virus
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