Uniink: A new 3D bioprinted cell therapy approach for Type 1 diabetes

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Uniink: A new 3D bioprinted cell therapy approach for Type 1 diabetes
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Javier Ramón Azcón, an ICREA research professor and the leader of the Biosensors for Bioengineering group at the Institute for Bioengineering of Catalonia (IBEC), has been granted an 'ERC Proof of Concept Grant.'

Reviewed by Danielle Ellis, B.Sc.Sep 18 2023 Javier Ramón Azcón, an ICREA research professor and the leader of the Biosensors for Bioengineering group at the Institute for Bioengineering of Catalonia , has been granted an "ERC Proof of Concept Grant." This prestigious grant is awarded by the European Research Council and aims to explore the commercial and societal potential of research projects that have been previously funded by the ERC.

Type 1 diabetes is a condition in which the immune system itself destroys the β cells of the pancreas, which are responsible for producing insulin, a hormone involved in the control of blood glucose. Uniink is presented as an evolution of this type of therapy. The project introduces an innovative 3D bioprinting method for manufacturing substantial quantities of biocompatible microspheres loaded with cells that can secrete insulin in response to external glucose signals. The incorporation of physical barriers, such as encapsulation, serves to shield the transplanted cells from the host's immune system.

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