Science, Space and Technology News 2024
Scientists propose a “protein aggregation clock” as a new method to assess aging and health by monitoring protein clumps in cells. This concept, if developed into a diagnostic tool, could enable early detection of age-related diseases and assessment of new treatments aimed at reducing protein aggregation. The protein aggregation clock could complement existing genetic-based biological clocks by providing a protein-focused perspective on cellular health and aging. Credit: SciTechDaily.
Could measuring protein clumps in our cells become a novel method to assess our risk of age-related diseases? Professors Dorothee Dormann and Edward Lemke from, who also serve as adjunct directors at the Institute of Molecular Biology in Mainz, suggest the idea of a “protein aggregation clock” for gauging aging and health.
“In practice, we are still far away from a routine diagnostic test, and it is important that we improve our understanding of the fundamental mechanisms leading to IDP aggregation”, said Dormann. “However, we want to stimulate thinking and research in the direction of studying protein aggregates to measure biological aging processes,” Lemke added.
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