When E. coli detects damage to its genetic material, it sends out an SOS signal that alters activity inside the cells.
Norwegian University of Science and Technology Jun 20 2024
Ciprofloxacin is currently one of the most widely used antibiotics in the world, and works by attacking the DNA in the bacterial cells. "The DNA is then damaged, including the formation of single strands of incomplete DNA inside the cell," says Bergum. Related StoriesKnowing exactly how the repair processes and mutation take place is important in order to counteract antimicrobial resistance. Bergum and her colleagues have therefore chosen to look at both how the 'SOS genes' are activated and how the bacteria use proteins and small molecules to repair the damage caused by the antibiotic.
Antibiotic Antimicrobial Resistance Bacteria Cell Ciprofloxacin DNA Doctor Gene Genes Genetic Medicine Pain Polymerase Protein Research Small Molecules Sore Throat Stress Technology Throat
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