When prostate cancer strikes, one question is paramount: Is it aggressive and requiring immediate treatment, or slow-growing and worthy of monitoring only? Right now, an invasive biopsy is the only way to answer that query, but researchers say they've developed a urine test...
When prostate cancer strikes, one question is paramount: Is it aggressive and requiring immediate treatment, or slow-growing and worthy of monitoring only?
“If you’re negative on this test, it’s almost certain that you don’t have aggressive prostate cancer,” said Dr. Arul Chinnaiyan, a professor of pathology and urology at Michigan Medicine. In decades past, the prostate-specific antigen blood test was used routinely to help spot cancers. But its inefficiency in differentiating between aggressive and slow-growing tumors led to over-treatment, and the test is now used much less frequently.
Prostate cancers' level of aggression is measured on what's called the Gleason score, with tumors scoring as Gleason Grade Group 2 or higher more likely to grow and spread than those rated Grade Group 1 , which may remain "indolent" for years. “Four of 10 men who would have a negative biopsy will have a low risk MPS2 result and can confidently skip a biopsy," Wei said.
Cancer Urine Test Genes Gleason Score Biopsy Invasive
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