Researchers at Weill Cornell Medicine with an international team have used liver biopsies to identify cellular and molecular markers that can potentially be used to predict whether and when pancreatic cancer will spread to an individual's liver or elsewhere, such as the lung.
Weill Cornell Medicine Jun 28 2024 Researchers at Weill Cornell Medicine with an international team have used liver biopsies to identify cellular and molecular markers that can potentially be used to predict whether and when pancreatic cancer will spread to an individual's liver or elsewhere, such as the lung.
If we can predict the timing and location of metastases, that could be a real game changer in treating pancreatic cancer, particularly patients at high metastatic risk." To find out how these alterations prime their new location for cancerous colonization, Dr. Lyden collaborated with lead author Dr. Linda Bojmar, an adjunct assistant professor of molecular biology research in pediatrics at Weill Cornell Medicine and assistant professor of clinical and experimental medicine at Linköping University in Sweden.
Related StoriesAt the other end of the spectrum were those who developed liver metastases within six months of diagnosis-;a patient group that has poor prognosis with limited therapeutic options. Their livers were riddled with so-called neutrophil extracellular traps , dense tangles of DNA and enzymes released by dying neutrophils, immune cells that are a first line of defense against infection.
Metastasis Pancreatic Cancer Biopsy DNA Fatty Liver Immune Response Liver Medicine Pediatrics
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