Uterine fibroid growth activated by chemicals found in everyday products northwesternu PNASNews
, and they've also been detected in medical supplies and food. Although they are known to be toxic, they are currently unbanned in the U.S.
"These toxic pollutants are everywhere, including food packaging, hair and makeup products, and more, and their usage is not banned," said corresponding study author Dr. Serdar Bulun, chair of the department of obstetrics and gynecology at Northwestern University Feinberg School of Medicine and a Northwestern Medicine physician."These are more than simply environmental pollutants. They can cause specific harm to human tissues.
Up to 80% of all women may develop a fibroid tumor during their lifetime, Bulun said. One-quarter of these women become symptomatic with excessive and uncontrolled uterine bleeding, anemia, miscarriages, infertility and large abdominal tumors necessitating technically difficult surgeries. The new study found women with a high exposure to certain phthalates such as DEHP and its metabolites have a high risk for having a symptomatic fibroid.phthalate
exposure and uterine fibroid growth, but this study explains the mechanisms behind that link. The scientists discovered exposure to DEHP may activate a hormonal pathway that activates an environmentally responsive receptor to bind to DNA and cause increased growth of fibroid tumors.," Bulun said."The use of agent orange during the Vietnam war caused significant reproductive abnormalities in the exposed populations; and dioxin and AHR were thought to be responsible for this.
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