UVA researchers identify a potential treatment for respiratory symptoms of long COVID

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UVA researchers identify a potential treatment for respiratory symptoms of long COVID
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University of Virginia School of Medicine researchers have identified a potential treatment for the respiratory symptoms of long COVID after discovering an unknown cause of the condition inside the lungs.

University of Virginia Health SystemJul 30 2024

Our study identified a root cause of the respiratory complication of long COVID by performing comparative analysis of both clinical samples and a relevant animal model. We hope that the identification of the 'driving' mechanisms will help to rationally design clinical studies repurposing those FDA-approved drugs for respiratory long COVID soon."

Prior research into long COVID has sought answers in patients' blood, but Sun and his team wanted to see what changes were taking place in the lung tissues themselves. So the UVA researchers looked at cell samples collected from the lower airways of both lab mice and human patients. In both cases, they found that immune cells known as macrophages and T cells had gone haywire and were having faulty, harmful interactions.

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