Breastcancer risk models may incorrectly classify many women journalgim
Breast cancer risk models guide screening and chemoprevention decisions, but the extent and effect of variability among models, particularly at the individual level, is uncertain.To quantify the accuracy and disagreement between commonly used risk models in categorizing individual women as average vs. high risk for developing invasive breast cancer.
Almost half of the women were classified as high risk by at least one of the three models for the threshold of ≥ 1.67%, and 11.1% were classified as high risk for ≥ 3.0%. All three models had similar accuracy at the population level.Breast cancer risk estimates for individual women vary substantially, depending on which risk assessment model is used.
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