Jefferson left the game in the third quarter after taking a hard hit to his right quadriceps.
with a quad injury and didn't return. After the game, Vikings head coach Kevin O'Connell provided an ecouraging update that makes it seem like Jefferson will be good to go when the Vikings aim to start 3-0 when they host the Houston Texans next Sunday.
"It was a quad contusion," O'Connell said at the postgame press conference podium. "Just got a little leg-to-leg contact on that. It's pretty sore, but he's already up and moving. We'll just treat that thing and hopeful he'll be day to day and we'll see how his status looks for next week." Jefferson lit up the 49ers with four catches for 132 yards and a touchdown that went 97 yards as he beat double coverage and Sam Darnold lofted a pass from the end zone to near midfield and Jefferson ran and dodges defenders on his way to the end zone.
The Vikings were already without No. 2 receiver Jordan Addison, whose ankle injury in Week 1 against the Giants coupled with Jefferson's quad injury left Darnold operating for the final 20+ minutes with Jalen Nailor, Brandon Powell, Trent Sherfield Sr. and Trishton Jackson.
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