Study evaluates the impact of vitamin D supplementation on bone health and cardiovascular risk factors in hypertensive patients, finding no significant improvements except in PTH levels, highlighting the complexity of vitamin D metabolism.
By Vijay Kumar MalesuMar 17 2024Reviewed by Susha Cheriyedath, M.Sc. In a recent study published in the journal Nutrients, researchers evaluated whether the "functional vitamin D deficiency" classification predicts the benefit of vitamin D supplementation on bone and cardiovascular health.
About the study The present study was a precisely designed, double-blind, placebo-controlled trial targeting 200 hypertensive patients with low serum 25D levels, specifically those under 75 nmol/L. This initiative was part of a larger screening effort, the Styrian Hypertension Study, which evaluated 518 participants to identify suitable candidates for the randomized controlled trial .
Study results In the study, data on the VMR were precisely collected for 505 individuals out of the initial 518. Among these, 192 were identified with vitamin D deficiency, indicated by 25D levels falling below 50 nmol/L. This distinction set the stage for an in-depth exploration of vitamin D metabolites and their health implications, with the participants' baseline characteristics thoroughly cataloged and stratified based on their 25D concentrations.
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