Thirteen years on from losing their nine-year-old son to cancer, Nicola and Dave Hulme are now part of a clinical trial to find a cure for B-cell Non-Hodgkin Lymphoma
Just six months after being diagnosed with B-cell Non-Hodgkin Lymphoma , nine-year-old Alex Hulme passed away leaving his family utterly devastated.
Children who have not responded to treatment for B-cell Non-Hodgkin Lymphoma , or who have relapsed, can sign up for Glo-BNHL, a global clinical trial run by the University of Birmingham.Multiple new treatments to offer a better chance of survival to hundreds of young people across the world will be tested over the next few years as part of the trial.
The trial has been seven years in the making following a meeting between academics, regulators, patient advocates and drug companies in 2017. It was decided to create a trial to study multiple treatments simultaneously so there was no competition between drugs, switching from one to another if one does not work, meaning that there should always be at least one new drug for any child with relapsed or refractory B-NHL.
The first sites have opened in the UK and awaiting the first of 210 patients who will test the drugs over the next seven years. Glo-BNHL will eventually open at 45 sites across 19 countries in Europe, Asia, North America and Australia. Alex’s mum Nicola, 56, said: “The only option left was a bone marrow transplant and a donor with a 100 per cent match was found, but it was too late by that stage as the cancer was too aggressive.”
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