The pharmacological effects of the components of Lycium ruthenicum Murray fruits.
By Pooja Toshniwal PahariaSep 29 2023Reviewed by Lily Ramsey, LLM In a recent review published in the Nutrients Journal, researchers reviewed existing data on the pharmacological and biological effects of the components of Lycium ruthenicum Murray fruits such as black goji berries.
About the review In the present review, researchers described the health benefits of consuming LRM based on studies retrieved from PubMed, Web of Science, and Google Scholar, published in English. In addition, LRM consumption helps prevent fatigue, obesity, diabetes, and influenza virus infections. In human breast cells, LRM fruit extracts have demonstrated antiproliferative activity and the activation of p21, p53, cyclin E, cyclin-dependent kinase 4 , caspase3, and Bcl-2-associated X protein .
Polysaccharides in LRM can reduce pancreatic cell proliferation, tumor size, tumor weight, Ki67, the cluster of differentiation 31 , phosphorylated glycogen synthase kinase 3β , B cell lymphoma 2 , phosphorylated protein kinase B , phosphorylated focal adhesion kinase , β-Catenin, p-P38, and caspase-3 and nine levels, and increase apoptosis. Polysaccharide intake can inhibit replication by arrest by resting phase -growth 1 phase .
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