What is the SARS-CoV-2 transmissibility among United States residents? medrxivpreprint LosAlamosNatLab SARSCoV2 COVID19 Coronavirus Transmissibility US UnitedStates
By Pooja Toshniwal PahariaSep 20 2022Reviewed by Aimee Molineux In a recent study posted to the medRxiv* preprint server, researchers estimated region-specific basic reproduction number values for MSAs in the US based on compartmental modeling with reproduced severe acute syndrome coronavirus 2 surveillance data.
About the study In the present study, researchers used their previously developed model to estimate regional COVID-19 R0 estimates for 280 out of 384 US MSAs, accounting for 95% and 82% of the US population residing in urban regions and the total population, respectively. The three variability measures were plotted as a function of the epidemiological week for the chosen MSAs and overlapping states. Histograms of time-averaged variability measures for multi-county MSAs and states were analyzed. For every MSA, the Bayesian inference approach, enabled by the MCMC sampling procedure, was applied to derive the maximum a posteriori R0 estimates, equivalent to the maximum likelihood estimates.
The disparate R0 estimates indicated that the population features contributing to the initial spread of SARS-CoV-2 were heterogeneous geographically and combined to yield >4-fold contagiousness of SARS-CoV-2. The variability measures were lesser for the MSAs in comparison to those for overlapping states.
United Kingdom Latest News, United Kingdom Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Endogenous exosomes act as decoys for SARS-CoV-2Endogenous exosomes act as decoys for SARS-CoV-2 Exosomes SARSCoV2 Coronavirus Disease COVID Tolllikereceptors Autophagic Interferons PLOSBiology UZH_ch UZH_Virology
Read more »
New mechanistic insights on the origin of SARS-CoV-2-induced neurological disordersNew mechanistic insights on the origin of SARS-CoV-2-induced neurological disorders biorxivpreprint umontpellier IRIM_life unistra SARSCoV2 COVID19 coronavirus neurological disease disorder
Read more »
The potential of nanobody engineering in the development of SARS-CoV-2 antivirals and diagnostic toolsThe potential of nanobody engineering in the development of SARS-CoV-2 antivirals and diagnostic tools biorxivpreprint helsinkiuni UZH_en LivUni nanobody SARSCoV2 antiviral covid coronavirus covid diagnosis
Read more »
Is there any impact of COVID-19 vaccines on the fertility of men and women of reproductive age?Is there any impact of COVID-19 vaccines on the fertility of men and women of reproductive age? Unicatt COVID19 coronavirus covid ferility SARSCoV2 reproductivehealth
Read more »
Molecular engineered low-cost highly effective RBD-based COVID vaccineIn a recent study posted to the bioRxiv* preprint server, an international team of researchers developed a second-generation severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor binding domain (RBD) antigen (RBD-J6) by molecular engineering with two additional amino acid (aa) substitutions (S383D and L518D mutations) in a hydrophobic cryptic RBD core epitope to enhance stability and expression against SARS-CoV-2 variants of concern (VOCs).
Read more »
The relationship between antigen concentration and diagnostic test performance for SARS-CoV-2 on different types of samplesThe relationship between antigen concentration and diagnostic test performance for SARS-CoV-2 on different types of samples medrxivpreprint PPI_Insights UW SARSCoV2 COVID19 coronavirus covid antigen diagnostictest
Read more »