Front-line work in public hospital ERs in Seattle, Memphis and Atlanta convinced me that the best way to treat life threatening emergencies - and to deliver healthcare in general - is to keep people as healthy as possible through public health and prevention.
The respective trajectories of two medications – one that helps obese people lose weight, the other highly effective at preventing heart attacks and strokes – illustrate the forces driving biomedical innovation in the United States.obesity. It should be used with a weight loss plan and physical activity. last August that Wegovy , its new weight loss drug, reduces heart attacks, strokes, and heart-related deaths by 20%, the news sparked worldwide coverage.
Photo provided by Dr. David Misselbrook, a retired GP in the UK. Reproduced with permission of BJGP Life Simple in concept, the pill works remarkably well. If every eligible person took a polypill every day, about two-thirds of heart attacks and strokes could be prevented. However, in real life, medication adherence is substantially less than 100%. In 2021, a pooledof 3 international randomized trials involving more than 18,000 participants found that compared to usual care, a once-daily polypill reduced new heart attacks and strokes by 38%.
As for the polypill, perhaps the rising toll of cardiovascular disease in the U.S. and globally will prompt reconsideration of its potential. In a Washington Postearlier this year, former CDC Director Tom Frieden wrote, “Hypertension, the ‘silent killer,’ is the deadliest but most neglected and widespread pandemic of our time, killing more than 10 million people a year worldwide.
While working at RAND from 2000 to 2003, Dr. Kellermann participated with teams that examined economic and policy forces that influence development and uptake of health technology in the U.S. After leaving RAND, he wrote about the polypill in two medical journal commentaries and a third public-facing one. His views are his own.Our community is about connecting people through open and thoughtful conversations. We want our readers to share their views and exchange ideas and facts in a safe space.
Healthcare Costs GLP-1 Wegovy Mounjaro FDA Compounding Pharmacies Medical Technology Polypill Ozempic
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