I am a postdoctoral research scientist focusing on childhood cancers and new, targeted cancer therapies. As a survivor of childhood leukemia myself, I am a determined advocate for research into better, less-toxic cancer treatments and how to reduce the long-term side effects of current drugs.
to other treatments. But now the FDA is concerned that the cellular therapy might be linked to the development of secondary cancers in a small number of patients.saying it was investigating reports of secondary cancers in people with blood cancers who were treated with CAR T cells.
Although the therapy has not been used on millions of people yet, it has been very successful in many indications, giving long-term remissions to people who would otherwise have likely not survived. So why is the FDA concerned that the therapy might actually be causing cancer in a small number of patients?
It's important to note that many conventional treatments for cancer can increase the risk of secondary cancers, sometimes many years down the line. Radiation therapy in particular increases the risk of future cancer development as it can damage the DNA of healthy cells. Some chemotherapy drugs also similarly increase the risk of secondary cancers.
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