Social-media platforms like TikTok are full of people conducting their own one-person trials of what they’re calling “nature’s Ozempic.” Here's why it's not:
found that when people took about 500 mg of berberine daily, they lost just about four pounds on average, even when sticking with the regimen for months. That’s a paltry amount compared to semaglutide, which can cause users to lose an average ofin around six months.
Diarrhea can lead to marginal weight loss in multiple ways—not just by getting rid of what’s in the bowels, but also because people may feel too uncomfortable to want to eat. Mughal compares this to taking shots of apple cider vinegar, another popular weight-loss trick that works because pouring vinegar into an empty stomach tends to make people too nauseated to eat. This is akin to laxative-based dieting, which is not the same as a true appetite suppressant and is much more taxing on the body.
“People need to realize that weight-loss medications that are prescribed are completely different from supplements,” says Mughal. “With true weight-loss medications, you can literally just take the medication, not do anything else, and you will lose weight.” But many supplements rely on other changes, like diet and exercise, to have any real effect. “Just taking berberine by itself, without addressing anything else, is likely not going to do anything,” he says.
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