The anti-cholesterol pills taken by millions of people to reduce the risk of a heart attack or stroke may also keep cancer at bay.
Statins, which are pills created to reduce cholesterol and the risk of a heart attack or stroke, may also prevent cancer by blocking an inflammatory protein, American scientists have said.
"We investigated the mechanism by which environmental toxins drive the initiation of cancer-prone chronic inflammation in the skin and pancreas. The scientists' cell-based experiments showed that environmental toxins - such as chemical irritants and an exposure to allergens - activate two connected signalling pathways. These are called the TLR3/4 and TBK1-IRF3 pathways.
In mice, the pitavastatin suppressed the environmentally-induced inflammation in the skin and pancreas, and in turn stopped the development of inflammation-related pancreatic cancers. The research team say that their findings show that blocking IL-33 production with pitavastatin may be a "safe and effective" way to suppress chronic inflammation and the subsequent development of certain cancers.
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