Meta-analysis shows association between autism in children and cardiometabolic diseases texastech JAMAPeds
Are individuals with autism at a higher associated risk of developing cardiometabolic diseases, including diabetes, hypertension, dyslipidemia, and macrovascular atherosclerotic disease?In this systematic review and meta-analysis of 34 studies that included 276 173 participants with autism and 7 733 306 participants without autism, individuals with autism had a higher associated risk of developing diabetes, dyslipidemia, and heart disease, but not hypertension or stroke.
Observational or baseline data of interventional studies reporting the prevalence of cardiometabolic risk factors among children and/or adults with autism and matched with participants without autism were included.Screening, data extraction, and quality assessment were performed independently by at least 2 researchers. DerSimonian-Laird random-effects meta-analyses were performed using the meta package in R.
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