A new study led by Lund University in Sweden has solved a years-old mystery: which patients with aggressive breast cancer are helped by a targeted cancer treatment that had been under development but was shelved.
Lund UniversityDec 4 2024 The study is important since it brings hope that the development of the drug can continue and that it will make it all the way to these patients.
It was a great disappointment to many of us in the field. We saw clear results in pre-clinical trials, but when we looked at entire patient cohorts it was not possible to draw firm conclusions. So, when I saw the results from the research group in Sweden, whose analysis came up with the answer as to which marker identified those who benefited from the drug, I was very pleasantly surprised.
The aim was to see if it was possible to find any marker that the patients who were helped by the treatment had in common. Surprisingly, it did not matter whether or not the tumor had the receptor the medicine is supposed to block on the cell surface.
Cancer Cancer Treatment Biomarker Medicine Protein Receptor Research
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