Just days before his fourth birthday, Santiago was diagnosed with B-cell acute lymphoblastic leukemia (B-ALL), the most common cancer in children.
The Hospital for Sick ChildrenDec 9 2024 Just days before his fourth birthday, Santiago was diagnosed with B-cell acute lymphoblastic leukemia , the most common cancer in children.
Early study results were so promising that the trial closed early, with findings published in the New England Journal of Medicine showing a striking 61 per cent reduction in the risk of B-ALL relapse or death for those who received both chemotherapy and blinatumomab. Reducing relapse – and side effects Before he joined the trial, Santiago received a combination therapy of steroids and chemotherapy, already personalized based on a genetic analysis of his leukemia cells showing which medications would be most effective for him.
Related Stories"These findings underscore the progress made with blinatumomab in preventing relapse and support its role as a critical addition to current therapeutic strategies," says study co-lead Dr. Rachel Rau, paediatric hematologist-oncologist at Seattle Children's Hospital and associate professor of pediatrics at the University of Washington.
Leukemia Acute Lymphoblastic Leukemia Cancer Cell Chemotherapy Children Hospital Immune System Immunotherapy Medicine Oncology
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