itemprop=description content=The association between substandard or falsified (SF) antibiotics and antimicrobial resistance (AMR).
By Pooja Toshniwal PahariaOct 5 2023Reviewed by Lily Ramsey, LLM In a recent review published in Nature Communications, researchers reviewed existing data on the association between substandard or falsified antibiotics and antimicrobial resistance .
About the review In the present review, researchers describe the impact of SF antibiotic usage on AMR. Furthermore, by decreasing the duration of therapy, the harsh chemotherapy method minimizes the selection window for the emergence of resistant mutants. A larger dose, on the other hand, provides a stronger selection advantage to resistant mutants.
The impact of substandard antibiotics on AMR is determined by the volume and bioavailability of the active pharmaceutical ingredients in the usual course of treatment with supreme-quality antimicrobials and how these changes in SF medicine. Nonetheless, clinical effects are likely to be substantially poorer. Since the connection between the ARM rate and dosage is likely biased in favor of AMR, only significant or entire decreases in the API content could result in AMR.
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