A study carried out at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid, Spain provides crucial information about the effect of cardiometabolic risk factors and subclinical atherosclerosis on the network of microvessels that irrigate the heart in symptom-free middle-aged individuals.
Cardiometabolic risk factors in apparently healthy individuals linked to altered coronary microcirculationCardiovascular risk factors alter coronary microvascular function and increase the risk of atherosclerotic disease, which itself leads to changes in the coronary microcirculation. Credit: CNIC
"Our findings suggest that coronary microvascular function could play a crucial role in the prediction of long-term cardiovascular risk in apparently healthy individuals," explained Dr. Ana Devesa, first author on the study."Physicians should consider the use of microvascular dysfunction as an early marker in the assessment of cardiovascular risk."
Dr. Valentín Fuster, CNIC General Director and leader of the PESA study, stressed the clinical implications of the results,"Our results show that coronary microvascular dysfunction is a key indicator that should be considered in routine clinical practice. These findings could lead to changes in the way we monitor and treat people with cardiometabolic risk factors, even before they show symptoms of cardiovascular disease.
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