Lewy body disease may be more common in middle-aged people than previously thought, according to a recent study. In the study, almost one in ten of over 50-year-olds were found to have tissue markers of Lewy body disease in the brain.
Lewy body disease is the second most common brain degenerative disease after Alzheimer's disease. Lewy bodies, deposits of alpha-synuclein protein, are found in the brainstem, limbic system and cerebral cortex. Similar tissue changes are also seen in patients clinically diagnosed with Parkinson's disease.
The researchers found that Lewy body disease changes may begin to develop in the brain already in middle age, even if there are no actual symptoms yet. "Finding out the prevalence of disease changes in younger age groups is therefore important as this will be the most effective time to start therapies," she comments.
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