'Our vaccine was able to effectively induce new variant-specific antibodies'
Scientists working on a new Covid vaccine say they have made a huge discovery, which could change booster jabs.
Researchers have tested their mRNA 'membrane-anchored receptor-binding domain' vaccine against older Covid vaccines, reports News.au. A report published in Molecular Therapy Methods and Clinical Development reads: "Waves of coronavirus infections resulting from the coronavirus disease 2019 pandemic are caused by mutants of the severe acute respiratory syndrome coronavirus 2 that evade humoral immunity previously acquired by way of either vaccination or viral infection.
"To reduce the incidence of COVID-related deaths, there is a need for broad-spectrum second-generation vaccines to protect elderly and vulnerable individuals from infection by emerging variants of SARS-CoV-2 or other known betacoronaviruses." "To address this, we developed an alternative platform designed to target SARS-CoV-2 virus mutations in the tip of the 'spike', otherwise known as the receptor binding domain. We found that, when administered as a third-dose booster following two doses of ancestral vaccine... our vaccine was able to effectively induce new variant-specific antibodies, making it a promising next-generation candidate to protect against new and emerging Covid-19 strains.
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