A Michigan Medicine-led study suggests that living in a disadvantaged community may decrease the length of time a person can survive with amyotrophic lateral sclerosis (ALS) by over 30%. The study, published in Neurology, found that people from the most disadvantaged neighborhoods had up to a 37% shorter survival time compared to those from the most resourced areas. Researchers used the Area Deprivation Index to measure neighborhood disadvantage, which considers factors like income, education, employment, and housing.
Michigan Medicine - University of MichiganFeb 7 2025 Living in a disadvantaged community may decrease the length of time a person can survive with amyotrophic lateral sclerosis, or ALS , by over 30%, a Michigan Medicine-led study suggests.While most people survive with ALS around two to four years, some people can live significantly longer.
"For years, we have defined the ALS 'exposome' as how environmental exposures over a lifetime affect a person's ALS risk and survival. The lived environment - in other words, the social exposome - is a key contributor to the overall exposome and is important to consider. Moreover, a deeper understanding of how socioeconomic factors contribute to ALS survival is important for making ALS a more livable disease and reducing the impact of health disparities.
"A person's social determinants of health may uniquely impact ALS due to the incredible costs of care, so it is important that we consider social factors and highlight the urgent need for interventions to reduce health disparities in ALS care," said first author Dae Gyu Jang, Ph.D., postdoctoral fellow in the U-M Health Department of Neurology.
ALS Survival Rate Socioeconomic Factors Health Disparities Social Determinants Of Health
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