Do COVID vaccines affect the menstrual cycle? COVID Coronavirus SARSCoV2 Vaccine WomensHealth menstrualcycle menstruation medrxivpreprint Apple NIEHS HarvardChanSPH
By Neha MathurJul 12 2022Reviewed by Emily Henderson, B.Sc. They focused their assessments on menstrual variations due to the type of coronavirus disease 2019 vaccine and the timing of its administration.
About the study In the present study, researchers used data from Apple's Women's Health Study to evaluate the temporal evolution of the relationship between COVID-19 vaccination and menstrual cycle length. They compared pre-vaccination menstrual cycle lengths, cycles in which a vaccine dose was administered, and cycles following COVID-19 vaccination.
Related StoriesFurther, the researchers included participant ID as a subject-level fixed effect in conditional linear regression models to estimate the covariate-adjusted within-woman difference and 95% confidence intervals in the mean cycle length. Finally, the model compared the vaccinated and post-vaccination cycles of each participating female to their pre-vaccine cycles .
All vaccinated females had only slightly longer menstrual cycles than their pre-vaccination cycles. On average, the single dose of the J&J vaccine increased the cycle length by 1.26 days. Further, the observed increase in the average length of menstrual cycles was negligible and non-persistent based on the number of vaccine doses . Moreover, menstrual cycle lengths returned to average pre-vaccination values within 0.14 days to -0.
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