Researchers at Duke University School of Medicine have found that tapping into the nervous system could help reduce the gut inflammation that drives inflammatory bowel disease (IBD).
Duke UniversityNov 20 2024 Research ers at Duke University School of Medicine have found that tapping into the nervous system could help reduce the gut inflammation that drives inflammatory bowel disease .
Modulating SUMOylation-;either through vagal nerve stimulation or treatment with a SUMOylation inhibitor-;could open the door to IBD therapies that focus on managing inflammation directly, rather than alleviating symptoms. One surprising finding of this study is that inhibiting SUMOylation appears to mimic the beneficial effects of vagal stimulation, resulting in improved clinical symptoms of colitis." IBD cases are soaring-;up 50% in the last 15 years. Scientists are intensifying efforts to reduce inflammation-causing cells in the intestines and improve treatment options for the nearly 7 million people affected worldwide.
Researchers have long noted that stress plays a significant role in exacerbating IBD symptoms, and some have even described ulcerative colitis as psychosomatic.
Nerve Anti-Inflammatory Brain Colon Crohn's Disease Inflammation Medicine Nervous System Research Stress Ulcerative Colitis
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