Existing advice for prescribing the weight loss drugs needs to be strengthened to minimize the risks from interactions, the European drug authority said.
; Orexigen Therapeutics Ireland Limited) and opioid-containing medicines. The recommendation followed a routine review of the safety of the weight loss medication.
The new recommendation is in addition to existing contraindications, which state that Mysimba must not be used in people who are dependent on long-term opioids, people receiving treatment with opioid agonists such as The treatment is used alongside diet and exercise to help manage weight in adults who have obesity or overweight and who have weight-related complications such as diabetes orIn three of the studies, the average weight loss was around 3.7%-5.7% in patients treated with Mysimba compared with 1.3%-1.9% in those treated with placebo. In the fourth study, in which patient counselling was more intensive, the overall weight loss was 8.1% with Mysimba and 4.9% with placebo.
Opioids Drug/Treatment Safety Drug Safety Treatment Safety Drug Interactions Drug Regulation Weight Loss Body Mass Index BMI Europe European Obesity Obese Bariatric Surgery Obesity Surgery Weight Loss Surgery Diet Increased Blood Pressure Hypertension Adverse Effects Side Effects Analgesia Analgesic Painkiller Blood Cough Tussis Exercise Physical Activity Grant
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