A new case series suggests that longer courses of Paxlovid may be beneficial for some individuals experiencing long COVID symptoms. The study highlights the need for further research to determine the optimal duration of treatment.
A recent study published in Communications Medicine explored the effects of prolonged oral nirmatrelvir/ritonavir (Paxlovid) treatment on individuals with long COVID. Long COVID, a multisystemic illness following COVID-19 , presents various symptoms like fatigue, brain fog, autonomic dysfunction, post-exertional malaise, tinnitus, headache, palpitations, blurred vision, taste/smell loss, chronic cough, chest pain, gastrointestinal issues, and changes in sexual capacity/desire.
Paxlovid, an oral antiviral, reduces viral activity and symptom severity in acute COVID-19. While some studies show symptom improvement after a five-day Paxlovid course, recurrence was observed in certain patients, suggesting the need for longer treatment durations. The study, focused on cases of long COVID patients on extended Paxlovid, identified participants through public forums and direct outreach. Individuals with a long COVID diagnosis who took Paxlovid for five days or more were included, ensuring they had clinically confirmed COVID-19 or positive test results.
PACLOVID LONG COVID COVID-19 TREATMENTS CASE STUDY
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