Fermented lingonberry juice shown to reduce inflammation and support gut health in IBD

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Fermented lingonberry juice shown to reduce inflammation and support gut health in IBD
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Fermented lingonberry juice may help manage inflammatory bowel disease (IBD) by modulating both the oral and gut microbiomes, reducing inflammation, and promoting beneficial bacteria.

By Dr. Chinta SidharthanReviewed by Susha Cheriyedath, M.Sc.Sep 2 2024 By targeting both the mouth and gut, fermented lingonberry juice harnesses potent bioactive compounds to curb microbial dysbiosis and protect against inflammation, offering a promising natural solution for managing IBD. Study: Oral Anti-Inflammatory and Symbiotic Effects of Fermented Lingonberry Juice—Potential Benefits in IBD.

Lingonberries are evergreen shrubs native to boreal forests and Arctic tundra across the Northern Hemisphere. Inflammatory bowel disease The excessive inflammation of the mucosal layer in the intestines characterizes inflammatory bowel disease. While the underlying causes are not known, alleles for specific genes, such as those coding for major histocompatibility complex , are known to increase the susceptibility to the disease.

Related StoriesBoth classes of IBD also manifest in oral symptoms, with aphthous stomatitis or canker sores and pyostomatitis vegetans, or pustules in the oral mucosa appearing in cases of ulcerative colitis. The oral symptoms of Crohn’s disease include mucogingivitis, bumps at the back of the throat, and tag-like lesions.

The study identifies specific bioactive compounds in lingonberries, including flavonoids, phenolic acids, and stilbenes, such as resveratrol, which are noted for their antimicrobial and anti-inflammatory effects. Fermentation also enzymatically breaks down large molecules into small ones, increasing the bioavailability of phenolic compounds and improving their absorption. Fermented lingonberry juice has been found to lower the levels of proteolytic inflammation in the oral cavity and selectively inhibit the growth of pathogens while promoting the growth of beneficial bacteria.

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