Hereditary changes in genes are often the cause of rare diseases. For example, disease-causing gene variants (PVs) in the HRAS gene cause Costello syndrome and PVs in the KRAS gene cause Noonan syndrome and cardio-facio-cutaneous syndrome.
Genetic mutations in HRAS, KRAS genes linked to childhood cancers retrieved 26 September 2024 from https://medicalxpress.com/news/2024-09-genetic-mutations-hras-kras-genes.html
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