Ask any neurologist: Parkinson's disease is a brain disorder. The conspicuous symptoms of Parkinson's disease-;uncontrollable tremors, slowed down motions, and the feeling that one's feet are stuck to the ground-;all stem from the loss of neurons in a region of the brain that helps control movement.
Reviewed by Danielle Ellis, B.Sc.Aug 22 2023 Ask any neurologist: Parkinson's disease is a brain disorder. The conspicuous symptoms of Parkinson's disease-; uncontrollable tremors, slowed down motions, and the feeling that one's feet are stuck to the ground-; all stem from the loss of neurons in a region of the brain that helps control movement.
"If this is the beginning of Parkinson's in many people, we could potentially identify who has the disease before it ever reaches the brain and hopefully stop it in its tracks," Sulzer says. The new findings were published Aug. 18 in Neuron. The blood of Parkinson's patients often contains immune cells that are primed to attack the neurons, but it's not clear where or when they are primed." The gut was an intriguing possibility because it contains the same neurons and because most Parkinson's patients experience constipation years before brain symptoms emerge and the disease is diagnosed.
"This shows that an autoimmune reaction can lead to what appears to be the early stages of Parkinson's and is strong support that Parkinson's is in part an autoimmune disease," Sulzer says.
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