Scientists reveal gut transit time and pH as key drivers of microbiome and metabolic individuality, paving the way for personalized dietary strategies.
By Vijay Kumar MalesuReviewed by Susha Cheriyedath, M.Sc.Dec 1 2024 How gut transit and pH shape the microbiome's role in metabolism and health, offering insights for personalized nutrition strategies.
Gut transit time has been shown to impact microbiome composition, with longer transit associated with increased microbial protein degradation and methane production. A nine-day observational study, “Personalized Dietary Recommendations based on the Interaction between Diet, Microbiome, and Abiotic Conditions in the Gut ,” was conducted at the University of Copenhagen between April and December 2021. It enrolled 63 healthy participants from Denmark.
Anthropometric measurements and a standardized meal test were also conducted. Metabolic profiling was performed on urine and fecal samples, and microbiome profiling used 16S ribosomal RNA sequencing. Participants also recorded daily 24-hour dietary records using the Myfood24 platform and noted bowel habits such as stool consistency , stool frequency, and time of defecation.
Ph Blood Coffee Diet Fasting Fatty Acids Metabolism Metabolites Microbiology Nutrition Physiology Protein Research Short-Chain Fatty Acids
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