A new study published in JAMA Network Open reveals that heavy lifetime cannabis use is associated with reduced brain activity during working memory tasks in young adults. The study, the largest of its kind, involved over 1,000 participants aged 22 to 36. Researchers found that 63% of heavy lifetime cannabis users exhibited reduced brain activity compared to non-users, while 68% of recent users also showed a similar impact. This decline in brain activity was linked to poorer performance on working memory tasks.
University of Colorado Anschutz Medical CampusJan 28 2025 A new study published today in JAMA Network Open explores the effects of both recent and lifetime cannabis use on brain function during cognitive tasks.
As cannabis use continues to grow globally, studying its effects on human health has become increasingly important. By doing so, we can provide a well-rounded understanding of both the benefits and risks of cannabis use, empowering people to make informed decisions and fully comprehend the potential consequences."
The researchers studied the neural response of participants during a magnetic resonance imaging session and gave them seven cognitive tasks to complete. The tasks tested working memory, reward, emotion, language, motor skills – such as tapping a finger to map brain control, relational assessment and theory of mind.
CANNABIS BRAIN FUNCTION WORKING MEMORY COGNITIVE TASKS HEALTH
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