Implantable sensors aid in optimizing bone injury recovery

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Implantable sensors aid in optimizing bone injury recovery
BoneExerciseMedicine
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Tiny implantable sensors are helping University of Oregon researchers optimize the process of recovery from severe bone injuries.

University of OregonDec 12 2024

The work is a collaboration between the labs of Bob Guldberg, Nick Willett and Keat Ghee Ong in the Knight Campus, and is funded in part by the Wu Tsai Human Performance Alliance. The researchers describe their findings Dec. 12 in the journal npj Regenerative Medicine. Specialized sensors developed at the Knight Campus could help change that by providing a window into what's happening inside a healing bone throughout recovery. Originally developed in a collaboration between the Ong and Guldberg labs, these sensors were further improved by recent doctoral graduate Kylie Williams.

Over the eight-week study, researchers monitored the healing process of the injured femurs and found that the resistance-trained rats displayed early signs of bone healing compared to those in sedentary or non-resistance conditions. By the end of the eight-week recovery period, all groups -; sedentary, non-resistance and resistance-trained -; showed bone healing.

Biological agents like BMP, a molecule that promotes bone growth, are often used in regeneration studies. However, Guldberg's team demonstrated complete functional recovery through resistance training alone, underscoring its potential for clinical application.

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