Investigators from Mass General Brigham have found that a method originally designed for cancer detection can also identify and monitor even tiny amounts of SARS-CoV-2 intact viral particles in blood and other fluids from patients with acute COVID-19 infections, creating the potential for guiding future treatment of patients.
Mass General BrighamJan 25 2025 Investigators from Mass General Brigham have found that a method originally designed for cancer detection can also identify and monitor even tiny amounts of SARS -CoV-2 intact viral particles in blood and other fluids from patients with acute COVID-19 infections, creating the potential for guiding future treatment of patients. The research is published in Science Advances.
Stott and colleagues in her lab, and the lab of Genevieve M. Boland, MD, PhD, surgical director of the Termeer Center for Targeted Therapies at MGH, found that their technique could detect as few as three viral particles in 1 milliliter of blood. When tested in more than 150 samples from patients with COVID-19, the method accurately measured virus levels across time, with intact viral particles detected as far out as 50 days after an initial infection.
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