A research team has unveiled a breakthrough in understanding how specific genetic sequences, known as pseudogenes, evolve.
Rice University's Peter Wolynes and his research team have unveiled a breakthrough in understanding how specific genetic sequences, known as pseudogenes, evolve. Their paper was published May 13 by theLed by Wolynes, the D.R.
However, the researchers observed instances where certain mutations unexpectedly stabilized the folding of pseudogenes at the cost of altering their previous biological functions. Using sophisticated computational models, the researchers interpreted the interplay between physical folding landscapes and the evolutionary landscapes of pseudogenes. Their findings provide evidence that the funnellike character of folding landscapes comes from evolution.
The implications of this research extend beyond theoretical biology with potential applications in protein engineering, Jaafari said.
Genes Forensics Amyotrophic Lateral Sclerosis Evolutionary Biology Genetics Molecular Biology Biology
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