IQWiG evaluates smoking cessation drugs for severe tobacco dependence treatment

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IQWiG evaluates smoking cessation drugs for severe tobacco dependence treatment
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By law, smokers with severe tobacco dependence are entitled to receive one-off drug therapy for smoking cessation as part of evidence-based programmes reimbursed by the German statutory health insurance (SHI).

Institute for Quality and Efficiency in Health Care Nov 27 2024 By law, smokers with severe tobacco dependence are entitled to receive one-off drug therapy for smoking cessation as part of evidence-based programs reimbursed by the German statutory health insurance .

There are no suitable published data on bupropion, cytisine or combination therapies for the subgroup analyses, and as no unpublished data were provided by the drug manufacturers, it is not possible to draw conclusions about their benefit. No assessment without evidence IQWiG repeatedly asked both the manufacturer of bupropion and the authors of study publications on cytisine for complete information, but to no avail. Therefore, it was not possible to carry out subgroup analyses on the severity of tobacco dependence to assess its influence on the study results for the two drugs. The advantages and disadvantages of these drugs for smokers with severe tobacco dependence are thus unclear.

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