A spoonful of sugar might actually help the medicine go down, according to recent research from the University of Mississippi. And it could reduce the harmful side effects of cancer treatment.
University of MississippiNov 21 2024
"They have a very narrow therapeutic window, meaning that the dose at which they work is very close to the dose at which they become toxic. And so as soon as you get enough dose for it to get rid of the tumor, it's also causing all this toxicity, all these off-target effects that you don't want. Werfel and Kenneth Hulugalla, a third-year doctoral student in biomedical engineering from Kandy, Sri Lanka, published their findings in ACS Nano in October.
When first used, it works extremely well. But after the first time, the body's immune system can recognize and tag the drug as foreign quickly. Once that happens, the drug can't get to the tumor and work. "Our findings highlight that the nanoparticles we're using significantly reduce unwanted immune responses while dramatically enhancing drug delivery, both in cell and animal models. This research could be an important step towards developing more effective cancer treatments.
Drug Delivery Breast Cancer Cancer Treatment Drugs Glucose Imaging Immune Response Immune System Medicine Nanoparticles Polymers Research Tumor
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