New blood test offers non-invasive way to detect heart transplant rejection

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New blood test offers non-invasive way to detect heart transplant rejection
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A blood test can show whether a new heart is tolerated by the recipient and not rejected. This has been shown in a thesis from the University of Gothenburg, Sweden.

University of GothenburgDec 17 2024 This means that heart transplant recipients can often avoid having tissue samples taken from their heart.

"The results are so clear that the new method will start to be used on patients, including those who have already had a heart transplant. We see in the study that DNA levels were usually very low, and that levels rose during rejection. This means that we can rule out rejection with a simple blood test," says Pediatric Cardiologist Jens Böhmer, who wrote the thesis at Sahlgrenska Academy at the University of Gothenburg.

Biopsies are very unpleasant and carry a risk for the patient. In addition, children undergo general anesthesia to take these samples." Today, taking biopsies from transplanted hearts is not only expensive, it also means that the recipient of a new heart has to travel, often long distances. In Sweden, heart transplants are performed in Gothenburg and Lund.

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